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Patient-Derived Tumor-on-a-chip

Tumor explant for drug development and translational oncology

 
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Add human relevance to your drug development

Our preclinical platform enables the ex vivo testing of anticancer agents on human tumors with their native tumor microenvironment (TME) preserved. We help biotech and pharmaceutical companies make better decisions by leveraging our patient-derived tumor model before they enter the clinic.

 

MISO Chip's microfluidic platform circumvents the usual limitations of primary tissue assays.

Human relevance

Undissociated, uniform tumor fragments (ø400µm) capture the heterogeneity of the primary tissue

 

Throughput

5 to 10x greater than standard explant models

 

Viability

World record of 15 days ex vivo without perfusion, that’s 5x longer than other explant platform

 

Services

Through a fee for service business model, we design custom studies for our clients to test their lead compounds with our tumor-on-a-chip technology.

  • Target Engagement and Pathway Modulation Studies

  • Drug Combination Testing

  • Efficacy Assays

  • Dosing Regimen Assessment

Products for Academia

Ex vivo Chips

MISO Chip offers its microfluidic devices to academic researchers in translational oncology. Whether its for following molecular pathways or developing predictive assays, our lab-on-chips provide a simple solution for 3D cell culture of micro-dissected tissues (MDT). No specialized equipment, no expensive reagents needed, our devices are handled with a standard pipette and enable users to quickly do their own ex vivo experiments.

In vitro Chips

MISO Chip also developed spheroid devices that can be used to cost-effectively grow large number of spheroids from your favorite cell line.

Contact us for product information.

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